Cobb Syndrome: New Case and Historical Review

Segmental cutaneous hemangioma and spinal arteriovenous malformation (Cobb syndrome). Case report and historical perspective.

The discovery of either a dermatomal cutaneous nevus or a spinal arteriovenous malformation (AVM) should raise the suspicion of Cobb syndrome. The Cobb syndrome is a neurocutaneous syndrome in which there are metameric cutaneous and spinal AVMs. The authors present the case of a patient with acute cervical myelopathy and subtle cutaneous hemangiomas in whom a cervical perimedullary fistula was ...

Neuro-vascular Abnormalities with a Metameric Nevus: A Case Report and Review of Cobb Syndrome

Cobb syndrome, also known as cutaneomeningospinal angiomatosis, first described by Berenbruch in 1890 and reported by Cobb in 1915, is a rare disorder characterized by spinal vascular malformations and a corresponding dermatomal vascular nevus. It usually presents in children and adults as lower extremity weakness, back pain, sensory loss below the affected level, or paralysis. Onset may be acu...

Cobb Syndrome: A Case Report with Review of Clinical and Imaging Findings

Cobb syndrome is a rare entity characterized by cutaneous vascular lesions and arteriovenous malformations in the spine, both in the same metamere. This syndrome is also known as cutaneous vertebral medullary angiomatosis, cutaneomeningospinal angiomatosis, and spinal arterial metameric disorder. We report the case of a male infant diagnosed with Cobb syndrome who was treated surgically. The pr...

[Historical and clinical review about Asperger syndrome].

A case report and a historical review

The purpose of this report is to present a short review of the history of Wilson’s disease and to describe the first diagnosed case at the Neurologic Clinic of Hospital das Clínicas of São Paulo University Medical School. The topics of the historical review are the first contributions of authors along the second half of the XIX century, the seminal monograph of Samuel Alexander Kinnier Wilson (...